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MicroRNA-194 regulates cell viability and apoptosis by targeting CDH2 in prostatic cancer.

Onco Targets Ther. 2018; 
GaoSong,ZhaoZhiying,WuRong,WuLina,TianXin,ZhangZhen
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Recombinant Proteins … Transfection. Cells were cultured for 24 h and seeded into 96-well plate for transfection. miR-194 mimic (20 nmol/L) and negative control (NC) (20 nmol/L) were purchased from Genscript (Shanghai, China) and were used according to manufacturer's protocol … Get A Quote

摘要

Prostate cancer (PCa) is one of the most common malignancies in men. However, a lack of understanding of the mechanism underlying PCa metastasis has strongly limited the effectiveness of therapy for this disease. Thus, investigating the mechanism of PCa may help improve the prognosis of PCa patients. The goal of this study was to investigate the role of microRNA-194 (miR-194) in PCa.

关键词

CDH2,apoptosis,cell viability,microRNA-194,prostatic ca